Ihr Milchbüchlein möchte ich sein – rank und schlank!
Was kostet den so eine Nebenwirkung:
Datenbestand der EMA 20.8.2021:
Bezeichner Anzahl Todesfälle Lebensbedr.ZwischenfälleHospitalisier.dyspnoea 32954 924 2318 7111chest pain 17660 212 1026 3916syncope 14002 136 485 1781tachycardia 11772 69 401 1682hypertension 9663 89 418 1665pulmonaryembolism9045 614 2821 5954chest discomfort 9045 36 323 1347muscle spasms 8638 13 127 573loss ofconsciousness8376 251 495 1476deep veinthrombosis6807 118 1093 2390anaphylacticreaction6752 30 1167 1986thrombosis 6173 312 970 2018seizure 5156 116 423 1488cerebrovascularaccident4942 418 1177 3196presyncope 4856 13 79 469vaccination failure 4609 204 63 449visual impairment 3994 19 96 591death 3951 3945 133 408thrombocytopenia 3929 328 882 2159facial paralysis 3701 16 113 922bell’s palsy 3476 1 23 470neuralgia 3096 2 31 261myocarditis 3090 62 421 2228haemorrhage 2911 62 159 354atrial fibrillation 2735 79 279 1141photophobia 2619 7 39 218swollen tongue 2571 5 247 358myocardialinfarction2329 584 700 1228Datenstand: 20.08.2021166Bezeichner Anzahl Todesfälle Lebensbedr.ZwischenfälleHospitalisier.pericarditis 2276 11 177 1124throat tightness 2259 1 215 375inflammation 2219 15 65 328petechiae 2066 17 113 447hallucination 2065 9 44 158transient ischaemicattack1934 23 244 996renal pain 1790 4 20 89guillain-barresyndrome1757 25 287 1306pharyngeal swelling 1745 3 213 262dysarthria 1620 43 165 680angina pectoris 1460 12 93 311deafness 1439 0 15 96ischaemic stroke 1438 119 314 1078cerebral infarction 1435 121 290 1096vaccinationcomplication1431 28 37 146aphasia 1428 60 190 647diplopia 1376 3 46 352cardiac arrest 1363 864 357 420fibrin d dimerincreased1337 39 114 438neuropathyperipheral1296 0 12 111unresponsive tostimuli1249 207 125 307hypertensive crisis 1233 10 60 262hemiparesis 1213 65 182 661abortionspontaneous1210 9 34 149facial paresis 1209 5 47 421depressed level ofconsciousness1170 88 107 324cerebralhaemorrhage1167 424 347 706paralysis 1163 19 83 344dyspnoea exertional 1154 22 91 317immunethrombocytopenia1144 38 274 741urinary tractinfection1132 55 54 330musculoskeletalchest pain1129 2 33 100platelet countdecreased1115 57 184 463Datenstand: 20.08.2021167Bezeichner Anzahl Todesfälle Lebensbedr.ZwischenfälleHospitalisier.loss of personalindependence indaily activities1098 4 52 166delirium 1090 25 50 187acute myocardialinfarction1071 224 369 741thrombophlebitissuperficial1044 4 43 137dysstasia 1035 7 47 235cardiac failure 1018 304 191 533blindness 1003 6 57 213anaphylactic shock 975 15 297 409cyanosis 898 55 60 165cerebral venoussinus thrombosis894 113 373 702cluster headache 882 4 11 43cardiovasculardisorder875 45 38 141cardiac flutter 873 2 18 58thrombophlebitis 851 6 43 98circulatory collapse 845 126 91 255panic attack 816 3 22 105sudden death 696 695 18 7haematochezia 695 6 15 104acute kidney injury 694 134 134 501deafness unilateral 680 0 3 36sensory loss 673 1 36 177sepsis 663 173 133 434anaemia 660 24 82 291photopsia 648 2 15 61sensation of foreignbody648 1 39 122monoplegia 622 6 21 114respiratory failure 595 218 152 368eye haemorrhage 589 1 5 33cardio-respiratoryarrest588 436 102 117pericardial effusion 579 25 92 351cardiac disorder 574 39 66 197embolism 561 45 144 230generalised tonicclonicseizure560 13 71 238bronchospasm 534 4 56 120haemoptysis 530 30 78 183pleural effusion 529 33 104 353hemiplegia 525 33 72 273Datenstand: 20.08.2021168Bezeichner Anzahl Todesfälle Lebensbedr.ZwischenfälleHospitalisier.venous thrombosislimb517 5 54 167rectal haemorrhage 510 14 23 113haematuria 492 7 25 100coagulopathy 491 38 80 152vasculitis 491 13 38 132pulmonarythrombosis470 32 172 370venous thrombosis 464 9 77 159polymyalgiarheumatica446 0 7 62phlebitis 440 0 14 59hypopnoea 436 10 34 54sinus tachycardia 435 5 27 142subarachnoidhaemorrhage425 110 170 282mouth swelling 425 2 30 43retinal veinocclusion407 0 2 43neurologicalsymptom405 11 35 164pulmonary oedema 402 93 89 224cerebral thrombosis 400 63 101 276renal failure 393 111 95 226monoparesis 371 3 19 75painful respiration 355 2 21 87allergy to vaccine 355 1 23 52respiratory arrest 355 173 83 113trigeminal neuralgia 349 0 2 41haematemesis 336 41 41 119motor dysfunction 332 9 18 105portal veinthrombosis332 39 91 249heart rate abnormal 330 3 10 49acute respiratoryfailure329 105 72 242blindness unilateral 328 2 18 93ventricularextrasystoles328 0 14 65visual field defect 326 0 10 79autoimmunedisorder323 5 19 64nerve injury 321 0 12 53white blood cellcount increased317 6 18 118labyrinthitis 316 1 3 38Datenstand: 20.08.2021169Bezeichner Anzahl Todesfälle Lebensbedr.ZwischenfälleHospitalisier.hospitalisation 305 11 4 293cerebral venousthrombosis300 41 101 199encephalitis 290 12 54 210immediate postinjectionreaction288 5 24 46internationalnormalised ratioincreased282 7 25 63hemiparaesthesia 279 1 3 47cardiac failurecongestive271 61 45 180blood urine present 271 4 9 40optic neuritis 270 0 2 112acute coronarysyndrome265 41 55 185myelitis transverse 264 1 18 172supraventriculartachycardia264 5 31 116colitis 259 2 16 95haemoglobindecreased258 12 30 103neutropenia 250 1 22 62pancreatitis acute 250 7 32 193diarrhoeahaemorrhagic238 3 14 45pancreatitis 237 9 28 131anaphylactoidreaction237 1 13 36blindness transient 236 0 8 33haemorrhagicstroke235 92 60 127rhabdomyolysis 231 9 34 163coma 230 63 79 107gastrointestinalhaemorrhage217 45 48 120anticoagulanttherapy217 9 109 184jaundice 214 13 16 112paresis 212 1 9 93atrial flutter 210 4 25 102giant cell arteritis 206 1 13 82mental disorder 203 2 9 46retinal arteryocclusion202 0 1 61multiple organ 202 130 47 99Datenstand: 20.08.2021170Bezeichner Anzahl Todesfälle Lebensbedr.ZwischenfälleHospitalisier.dysfunctionsyndromesystemic lupuserythematosus200 1 12 31myoclonus 199 2 8 50immune systemdisorder199 4 3 27pulmonaryinfarction198 11 73 140blood test abnormal 198 0 14 71renal impairment 193 18 20 75pleurisy 192 0 10 95internalhaemorrhage188 14 13 44activated partialthromboplastin timeprolonged185 4 50 78diplegia 184 2 15 49pleuritic pain 183 1 39 92cardiac failure acute 183 97 27 96ventriculartachycardia182 20 52 100alanineaminotransferaseincreased177 2 11 50mesenteric veinthrombosis175 20 55 134myelitis 174 1 7 126white blood cellcount decreased174 0 12 53encephalopathy 173 20 29 129brain oedema 173 49 50 93ventricularfibrillation172 68 74 84partial seizures 171 5 18 62peripheral arterythrombosis170 10 47 111kidney infection 169 2 15 49liver function testabnormal168 6 9 50cerebral ischaemia 166 17 29 100peripheralischaemia166 22 27 85choking sensation 166 1 16 30cutaneous vasculitis 166 2 2 59septic shock 163 87 36 96Datenstand: 20.08.2021171Bezeichner Anzahl Todesfälle Lebensbedr.ZwischenfälleHospitalisier.haemorrhageintracranial159 49 57 99leukopenia 157 6 12 55ischaemic cerebralinfarction156 14 57 119hepatitis 155 2 11 63hypovolaemic shock 153 13 12 22haemorrhageurinary tract152 2 9 24renal disorder 149 11 17 63retinal detachment 149 0 1 69suffocation feeling 147 0 19 20cardiogenic shock 146 70 50 72disseminatedintravascularcoagulation145 54 60 103hemianaesthesia 145 1 6 36meningitis 144 3 10 86liver disorder 142 6 14 54magnetic resonanceimaging headabnormal142 3 43 129intensive care 137 19 67 128subduralhaematoma135 17 51 97jugular veinthrombosis134 8 45 90myocardialischaemia134 66 13 45peripheralcirculatory failure133 3 2 36lymphopenia 133 3 13 42myasthenia gravis 133 2 6 54retinal veinthrombosis131 1 3 11loss of control oflegs131 0 4 27intestinal ischaemia 131 52 41 73hepatic functionabnormal130 6 9 70platelet countincreased129 0 9 17computerisedtomogram thoraxabnormal129 4 77 108coronary arterydisease128 30 19 79Datenstand: 20.08.2021172Bezeichner Anzahl Todesfälle Lebensbedr.ZwischenfälleHospitalisier.seizure likephenomena127 7 7 29red blood cellsedimentation rateincreased125 2 1 30ischaemia 125 12 29 70pancytopenia 123 11 31 92acute respiratorydistress syndrome122 54 32 75cardiomyopathy 121 11 31 67atelectasis 120 10 20 79atrioventricularblock118 5 37 72infarction 118 19 31 69colitis ischaemic 116 10 12 75embolic stroke 116 11 30 85nephrotic syndrome 115 1 4 64apnoea 115 31 14 23dysphemia 114 2 8 33internationalnormalised ratiodecreased114 1 9 14gaze palsy 113 5 11 28near deathexperience113 0 20 18demyelination 113 0 5 63systemicinflammatoryresponse syndrome112 14 23 67computerisedtomogram headabnormal111 12 46 105haemorrhoidsthrombosed111 0 1 10brain injury 110 35 32 55hepatic cytolysis 110 2 2 41coronary arterythrombosis109 23 59 61melaena 109 11 14 47stupor 108 4 5 10pelvic venousthrombosis108 4 34 67arterial thrombosis 108 12 35 59tachyarrhythmia 107 2 6 22laryngospasm 107 1 17 19intracardiac 106 26 34 68Datenstand: 20.08.2021173Bezeichner Anzahl Todesfälle Lebensbedr.ZwischenfälleHospitalisier.thrombusaspartateaminotransferaseincreased105 2 7 32coronary arteryocclusion104 13 48 80acute disseminatedencephalomyelitis104 3 17 87inflammatorymarker increased103 3 8 44tonic convulsion 102 1 9 40areflexia 99 3 12 77ultrasound scanabnormal99 1 11 23thromboticthrombocytopenicpurpura99 13 35 72superior sagittalsinus thrombosis98 17 49 73pneumothorax 98 7 18 63asphyxia 98 18 10 14lacunar infarction 97 1 18 64splenic infarction 96 12 14 71vith nerve paralysis 95 0 1 36blood fibrinogenincreased95 2 12 25arterial occlusivedisease94 4 17 58acute pulmonaryoedema93 19 17 59autonomic nervoussystem imbalance92 1 11 26endotrachealintubation92 27 41 77atrioventricularblock complete91 11 39 60aortic dissection 91 50 20 31subclavian veinthrombosis90 5 20 45red blood cell countdecreased89 3 5 27brain steminfarction88 11 19 72cerebellar infarction 88 7 27 68cardiac fibrillation 87 1 12 31meningitis aseptic 87 0 8 68ascites 86 14 14 53Datenstand: 20.08.2021174Bezeichner Anzahl Todesfälle Lebensbedr.ZwischenfälleHospitalisier.pulse absent 86 34 14 29cholecystitis 86 4 4 50pyelonephritis 85 6 4 44splenomegaly 85 2 7 46thrombocytopenicpurpura85 3 12 63ophthalmic veinthrombosis84 2 7 34hepatic failure 84 28 27 54foetal death 84 17 5 33stevens-johnsonsyndrome84 4 9 33arteriosclerosis 83 32 9 36peripheralembolism83 4 17 41resuscitation 81 45 26 36autoimmunehaemolytic anaemia81 5 15 60liver function testincreased81 2 7 23cerebral arteryocclusion81 12 22 66tonic clonicmovements81 0 7 17sudden cardiacdeath81 81 5 3intestinalobstruction79 15 7 39cerebellar stroke 79 2 20 61cerebral haematoma 78 20 25 61thalamic infarction 77 2 12 64cerebral arterythrombosis76 14 26 49haemolytic anaemia 76 5 16 48fibrin d dimer 75 0 20 35transverse sinusthrombosis75 6 21 55renal infarct 75 10 19 57computerisedtomogram abnormal74 1 22 46thunderclapheadache74 0 4 26hyporeflexia 73 0 10 32pulmonary fibrosis 72 9 7 35thrombocytosis 72 1 11 29liver injury 72 2 8 27Datenstand: 20.08.2021175Bezeichner Anzahl Todesfälle Lebensbedr.ZwischenfälleHospitalisier.lumbar puncture 72 0 18 64aortic thrombosis 72 15 29 48haematocritdecreased71 3 3 17cerebral arteryembolism71 12 30 50adrenocorticalinsufficiency acute71 1 20 28haemophagocyticlymphohistiocytosis70 11 36 59stresscardiomyopathy67 4 22 59embolism venous 67 5 10 37meningitis viral 65 1 4 42carotid arterythrombosis65 13 28 47cardiac tamponade 65 19 25 37left ventriculardysfunction64 6 18 43myocardial strain 64 4 33 50retinal vascularthrombosis64 1 3 21pulseless electricalactivity64 43 20 26heparin-inducedthrombocytopeniatest positive63 6 11 45thrombosis indevice63 2 21 29intracranialaneurysm62 17 20 44metabolic acidosis 62 18 20 39paraparesis 62 1 3 33haemolysis 61 5 11 30splenic veinthrombosis61 11 20 42carotid arteryocclusion60 6 17 44lacunar stroke 60 0 12 37miller fishersyndrome60 1 7 42aneurysm 60 11 13 34thrombectomy 60 7 25 51magnetic resonanceimaging abnormal58 1 19 40hypercoagulation 58 3 16 24Datenstand: 20.08.2021176Bezeichner Anzahl Todesfälle Lebensbedr.ZwischenfälleHospitalisier.cerebrovasculardisorder58 11 8 31bundle branch blockright57 0 14 28hemianopia 57 1 9 29hypertensiveemergency57 1 8 31urosepsis 56 20 9 39sopor 56 11 2 12csf proteinincreased55 0 9 50angiogram cerebralabnormal55 2 27 53lactic acidosis 54 12 9 39craniocerebralinjury53 8 6 26hepatic veinthrombosis53 7 12 37blood countabnormal52 0 6 19white matter lesion 52 0 8 37neutrophil countdecreased51 1 6 14haemorrhagicdiathesis50 2 6 12coma scaleabnormal50 13 17 30personality change 49 6 1 17brain death 49 42 14 23emphysema 47 9 3 15pulmonaryhaemorrhage47 12 16 31venous occlusion 46 2 4 27vena cavathrombosis46 6 16 29myocardial necrosismarker increased45 0 7 32coronary arterystenosis45 6 13 29intraventricularhaemorrhage45 12 19 31carotid arterystenosis44 5 7 36cerebral smallvessel ischaemicdisease44 2 4 31cardiac ventricular 44 6 21 34Datenstand: 20.08.2021177Bezeichner Anzahl Todesfälle Lebensbedr.ZwischenfälleHospitalisier.thrombosisgastrichaemorrhage44 10 9 21pulmonary arterythrombosis43 11 14 31thrombotic stroke 43 4 14 35computerisedtomogram headnormal41 1 8 37cardiovascularinsufficiency40 2 5 8visceral venousthrombosis40 6 18 30right ventricularfailure39 9 15 24bundle branch blockleft38 4 6 16apraxia 38 2 9 23basilar arterythrombosis37 9 16 24blood fibrinogendecreased37 2 16 24aortic aneurysm 37 12 4 15cardiopulmonaryfailure36 32 1 7retinal arterythrombosis36 0 2 4haemorrhagictransformationstroke35 12 13 26pupil fixed 34 8 7 12activated partialthromboplastin timeshortened33 1 9 18embolism arterial 33 1 11 23blood lactic acidincreased33 7 9 13brain stem stroke 32 4 8 19axillary veinthrombosis32 3 8 13mesenteric arterythrombosis32 11 7 18portosplenomesenteric venousthrombosis31 3 11 27ventriculararrhythmia31 2 12 11Datenstand: 20.08.2021178Bezeichner Anzahl Todesfälle Lebensbedr.ZwischenfälleHospitalisier.renal veinthrombosis29 3 13 19internationalnormalised ratioabnormal28 1 2 7cavernous sinusthrombosis28 7 11 18atrial thrombosis 27 4 15 21thromboticmicroangiopathy25 3 12 19vascular stentthrombosis22 2 11 17ovarian veinthrombosis21 3 6 13internationalnormalised ratio20 0 6 13thrombotic cerebralinfarction19 1 1 16seizure cluster 17 0 2 6splenic thrombosis 16 2 4 10thrombosismesenteric vessel16 5 5 10internationalnormalised ratiofluctuation16 0 1 2ophthalmic arterythrombosis15 0 0 4renal arterythrombosis15 0 3 12splenic arterythrombosis14 1 3 13vascular graftthrombosis14 2 3 9pulmonary venousthrombosis13 0 4 7thrombosedvaricose vein13 0 0 0brain stemthrombosis13 3 4 8vertebral arterythrombosis13 0 2 9hepatic vascularthrombosis12 3 3 9subclavian arterythrombosis11 1 4 7injection sitethrombosis10 0 0 2Datenstand: 20.08.2021179Bezeichner Anzahl Todesfälle Lebensbedr.ZwischenfälleHospitalisier.penile veinthrombosis10 0 1 0vaccination sitethrombosis9 0 2 1renal vascularthrombosis9 3 4 6brachiocephalic veinthrombosis9 0 4 3arteriovenousfistula thrombosis8 0 0 5hepatic arterythrombosis6 0 2 6truncus coeliacusthrombosis5 1 3 4cerebellar arterythrombosis4 0 1 2post thromboticsyndrome4 0 2 1adrenal thrombosis 3 1 1 3hypoglycaemicunconsciousness3 0 0 2endotrachealintubationcomplication2 0 1 2catheter sitethrombosis2 0 0 2spinal arterythrombosis2 0 0 1vascular access sitethrombosis2 0 0 1intracerebralhaematomaevacuation1 0 0 1arteriovenous graftthrombosis1 0 1 0infusion sitethrombosis1 0 0 0
