I want to be your little milk book – tall and slim!
How much does a side effect like this cost:
Data base of the EMA 20.8.2021:
Identifier Number of deaths Life-threatening incidentsHospitaliser.dyspnoea 32954 924 2318 7111chest pain 17660 212 1026 3916syncope 14002 136 485 1781tachycardia 11772 69 401 1682hypertension 9663 89 418 1665 pulmonary embolism 9045 614 2821 5954 chest discomfort 9045 36 323 1347 muscle spasms 8638 13 127 573 loss of consciousness 8376 251 495 1476 deep vein thrombosis 6807 118 1093 2390anaphylacticreaction6752 30 1167 1986thrombosis 6173 312 970 2018seizure 5156 116 423 1488cerebrovascularaccident4942 418 1177 3196presyncope 4856 13 79 469 vaccination failure 4609 204 63 449 visual impairment 3994 19 96 591 death 3951 3945 133 408 thrombocytopenia 3929 328 882 2159 facial paralysis 3701 16 113 922 bell's palsy 3476 1 23 470 neural gia 3096 2 31 261myocarditis 3090 62 421 2228haemorrhage 2911 62 159 354atrial fibrillation 2735 79 279 1141photophobia 2619 7 39 218swollen tongue 2571 5 247 358myocardialinfarction2329 584 700 1228Data status: 08/20/2021166Identifier Number of deaths Life-threatening incidentsHospitalize.pericarditis 2276 11 177 1124throat tightness 2259 1 215 375inflammation 2219 15 65 328petechiae 2066 17 113 447hallucination 2065 9 44 158transient ischemic attack1934 23 244 996renal pain 1790 4 20 89guillain-barresyndrome1757 25 287 1306pharyngeal swelling 1745 3 213 262dysarthria 1620 43 165 680angina pectoris 1460 12 93 311deafness 1439 0 15 96ischaemic stroke 1438 119 314 1078cerebral infarction 1435 121 290 1096vaccinationcomplication1431 28 37 146aphasia 1428 60 190 647diplopia 1376 3 46 352cardiac arrest 1363 864 357 420fibrin d dimerincreased1337 39 114 438neuropathyperipheral1296 0 12 111unresponsive tostimuli1249 207 125 307hypertensive crisis 1233 10 60 262hemiparesis 1213 65 182 661abortionspontaneous1210 9 34 149facial paresis 1209 5 47 421depressed level ofconsciousness1170 88 107 324 cerebral haemorrhage 1167 424 347 706 paralysis 1163 19 83 344 dyspnea exertional 1154 22 91 317 immune thrombocytopenia 1144 38 274 741 urinary tract infection 1132 55 54 330 musculoskeletal chest pain 1129 2 33 100platelet countdecreased1115 57 184 463Data status: 08/20/2021167Identifier Number of deaths Life-threatening incidentsHospitaliser.loss of personalindependence indaily activities1098 4 52 166delirium 1090 25 50 187 acute myocardial infarction 1071 224 369 741 thrombophlebitis superficial 1044 4 43 137 dysstasia 1035 7 47 235 cardiac failure 1018 304 191 533 blindness 1003 6 57 213 anaphylactic shock 975 15 297 4 09cyanosis 898 55 60 165cerebral venous sinus thrombosis894 113 373 702cluster headache 882 4 11 43cardiovasculardisorder875 45 38 141cardiac flutter 873 2 18 58thrombophlebitis 851 6 43 98circulatory collapse 845 126 91 255panic attack 816 3 22 105sudden death 696 695 18 7haematochezia 695 6 15 104acute kidney injury 694 134 134 501deafness unilateral 680 0 3 36sensory loss 673 1 36 177sepsis 663 173 133 434anaemia 660 24 82 291photopsia 648 2 15 61sensation of foreignbody648 1 39 122monoplegia 622 6 21 114respiratory failure 595 218 152 368eye haemorrhage 589 1 5 33cardio-respiratoryarrest 588 436 102 117pericardial effusion 579 25 92 351cardiac disorder 574 39 6 6 197embolism 561 45 144 230generalised tonicclonicseizure 560 13 71 238bronchospasm 534 4 56 120haemoptysis 530 30 78 183pleural effusion 529 33 104 353hemiplegia 525 33 72 273Data status: 08/20/2021168Identifier Number of deaths Life-threatening incidentsHospitaliser.venous thrombosislimb517 5 54 167rectal haemorrhage 510 14 23 113haematuria 492 7 25 1 00coagulopathy 491 38 80 152vasculitis 491 13 38 132pulmonary thrombosis 470 32 172 370venous thrombosis 464 9 77 159polymyalgiarheumatica 446 0 7 62phlebitis 440 0 14 59hypopnea 436 10 34 54sinus tachycardia 435 5 27 142subarachnoid haemorrhage425 110 170 282mouth swelling 425 2 30 43retinal veinocclusion407 0 2 43neurologicalsymptom405 11 35 164pulmonary edema 402 93 89 224cerebral thrombosis 400 63 101 276renal failure 393 111 95 226monoparesis 371 3 19 75painful respiration 355 2 21 87allergy to vaccine 355 1 23 52respiratory arrest 355 173 83 113trigeminal neuralgia 349 0 2 41haematemesis 336 41 41 119motor dysfunction 332 9 18 105portal veinthrombosis 332 39 91 249heart rate abnormal 330 3 1 0 49 acute respiratory failure 329 105 72 242 blindness unilateral 328 2 18 93 ventricular extrasystoles 328 0 14 65 visual field defect 326 0 10 79 autoimmune disorder 323 5 19 64 nerve injury 321 0 12 53 white blood cell count increased 317 6 18 118 labyrinthitis 316 1 3 38 data status: 20.08.2021169 identifier number of deaths life-threatening incidents hospitalize.hospitalization 305 11 4 293cerebral venous thrombosis 300 41 101 199encephalitis 290 12 54 210immediate postinjectionreaction288 5 24 46internationalnormalized ratioincreased282 7 25 63hemiparaesthesia 279 1 3 47cardiac failurecongestive271 61 45 180blood urine present 271 4 9 40optic neuritis 270 0 2 112acute coronarysyndrome265 41 55 185transverse myelitis 264 1 18 172supraventriculartachycardia264 5 31 116colitis 259 2 16 95haemoglobincreased258 12 30 103neutropenia 250 1 22 62pancreatitis acute 250 7 32 193diarrhoeahaemorrhagic238 3 14 45pancreatitis 237 9 28 131anaphylactoidreaction237 1 13 36blindness transient 236 0 8 33haemorrhagicstroke235 92 60 127rhabdomyolysis 231 9 34 163coma 230 63 79 107gastrointestinal haemorrhage217 45 48 120anticoagulanttherapy217 9 109 184jaundice 214 13 16 112paresis 212 1 9 93atrial flutter 210 4 25 102giant cell arteritis 206 1 13 82mental disorder 203 2 9 46retinal arteryocclusion 202 0 1 61multiple organ 202 130 47 99Data status: 20.08.2 021170Identifier Number of deaths Life-threatening incidentsHospitaliser.dysfunctionsyndromesystemic lupuserythematosus200 1 12 31myoclonus 199 2 8 50immune systemdisorder199 4 3 27pulmonary infarction198 11 73 140blood test abnormal 198 0 14 71renal impairment 193 18 20 75pleurisy 192 0 10 95internalhaemorrhage188 14 13 44activated partialthromboplastin timeprolonged185 4 5 0 78diplegia 184 2 15 49pleuritic pain 183 1 39 92cardiac failure acute 183 97 27 96ventriculartachycardia182 20 52 100alanineaminotransferaseincreased177 2 11 50mesenteric veinthrombosis175 20 55 134myelitis 174 1 7 126white blood cellcount decreased174 0 12 53encephalopathy 173 20 29 129brain edema 173 49 50 93ventricularfibrillation172 68 74 84partial seizures 171 5 18 62peripheral arterythrombosis170 10 47 111kidney infection 169 2 15 49liver function testabnormal168 6 9 50cerebral ischemia 166 17 29 100 peripheral ischemia 166 22 27 85 choking sensation 166 1 16 30 cutaneous vasculitis 166 2 2 59 septic shock 163 87 36 96 data status: 20.08.2021171 designator number of deaths life-threatening incidents hospitalization. haemorrhageintracranial 159 4 9 57 99leukopenia 157 6 12 55ischaemic cerebral infarction 156 14 57 119hepatitis 155 2 11 63hypovolaemic shock 153 13 12 22haemorrhageurinary tract152 2 9 24renal disorder 149 11 17 63retinal detachment 149 0 1 69suffocation feeling 147 0 19 20cardiogenic shock 146 70 50 72disseminatedintravascularcoagulation145 54 60 103hemianaesthesia 145 1 6 36meningitis 144 3 10 86liver disorder 142 6 14 54magnetic resonanceimaging headabnormal142 3 43 129intensive care 137 19 67 128subduralhaematoma135 17 51 97jugular veinthrombosis134 8 45 90myocardialischaemia134 66 13 45peripheralcirculatory failure133 3 2 36lymphopenia 133 3 13 42myasthenia gravis 133 2 6 54retinal veinthrombosis131 1 3 11loss of control of legs131 0 4 27intestinal ischemia 131 52 41 73hepatic functionabnormal130 6 9 70platelet countincreased129 0 9 17computerisedtomogram thoraxabnormal129 4 77 108 coronary arterydisease 128 30 19 79 data status: 20.08.2021172 identifier number of deaths life-threatening incidents hospitaliser. seizure like phenomena 127 7 7 29 red blood cells sedimentation rate increased 125 2 1 30 ischaemia 125 12 29 70 pancytopenia 123 11 31 92acute respiratory distress syndrome 122 54 32 75cardiomyopathy 121 11 31 67atelectasis 120 10 20 79atrioventricular block 118 5 37 72infarction 118 19 31 69colitis ischemic 116 10 12 75embolic stroke 116 11 30 85nephrotic syndrome 115 1 4 64apnea 115 31 14 23dysphemia 114 2 8 33internationalnormalized ratiodecreased 114 1 9 14gaze palsy 113 5 11 28 near death experience 113 0 20 18 demyelination 113 0 5 63 systemic inflammatory response syndrome 112 14 23 67 computerized tomogram head abnormal 111 12 46 105haemorrhoidsthrombosed111 0 1 10brain injury 110 35 32 55hepatic cytolysis 110 2 2 41coronary arterythrombosis109 23 59 61melaena 109 11 14 47stupor 108 4 5 10pelvic venous thrombosis108 4 34 67arterial thrombosis 108 12 35 59tachyarrhythmia 107 2 6 22laryngospasm 107 1 17 19intracardiac 106 26 34 68data status: 08/20/2021173Identifier Number of deaths Life-threatening incidentsHospitalis.thrombusaspartateaminotransferaseincreased105 2 7 32coronary arteryocclusion104 13 48 80acute disseminatedencephalomyelitis104 3 17 87inflammatorymarker increased103 3 8 44tonic convulsion 102 1 9 40areflexia 99 3 12 77ultrasound scanabnormal99 1 11 23 thromboticthrombocytopenicpurpura 99 13 35 72superior sagittal sinus thrombosis 98 17 49 73pneumothorax 98 7 18 63asphyxia 98 18 10 14lacunar infarction 97 1 18 64splenic i 7 atrioventricular block complete 91 11 39 60 aortic dissection 91 50 20 31 subclavian vein thrombosis 90 5 20 45 red blood cell count decreased 89 3 5 27 brain steminfarction88 11 19 72cerebellar infarction 88 7 27 68cardiac fibrillation 87 1 12 31meningitis aseptic 87 0 8 68ascites 86 14 14 53Data status: 20.08.2021174Identifier Number of deaths Life-threatening incidentsHospitalization.pulse absent 86 34 14 29cholecystitis 86 4 4 50pyelonephritis 85 6 4 44splenomegaly 85 2 7 46thrombocytopenicpurpura85 3 12 63ophthalmic veinthrombosis84 2 7 34hepatic failure 84 28 27 54foetal death 84 17 5 33stevens-johnsonsyndrome84 4 9 33arteriosclerosis 83 32 9 36peripheralembolism83 4 17 41resusc itation 81 45 26 36 autoimmune haemolytic anemia 81 5 15 60 liver function test increased 81 2 7 23 cerebral artery occlusion 81 12 22 66 tonic clonic movements 81 0 7 17sudden cardiac death81 81 5 3intestinalobstruction79 15 7 39cerebellar stroke 79 2 20 61cerebral haematoma 78 20 25 61thalamic infarction 77 2 12 64cerebral arterythrombosis 76 14 26 49haemolytic anemia 76 5 16 48fibr in d dimer 75 0 20 35transverse sinus thrombosis 75 6 21 55renal infarct 75 10 19 57computerised tomogram abnormal74 1 22 46thunderclapheadache74 0 4 26hyporeflexia 73 0 10 32pulmonary fibrosis 72 9 7 35thrombocytosis 72 1 11 29liver injury 72 2 8 27Data status: 20.08.2021175Identifier Number of deaths Life-threatening incidents Hospitalization.lumbar puncture 72 0 1 8 64aortic thrombosis 72 15 29 48haematocritdecreased 71 3 3 17cerebral arteryembolism 71 12 30 50adrenocortical insufficiency acute71 1 20 28haemophagocyticlymphohistiocytosis 70 11 36 59stresscardiomyopathy 67 4 22 59embolism venous 67 5 10 37meningitis viral 65 1 4 42carotid arterythrombosis 65 13 28 47cardiac tamponade 65 19 25 37left ventriculardy sfunction64 6 18 43myocardial strain 64 4 33 50retinal vascular thrombosis64 1 3 21pulseless electrical activity64 43 20 26heparin-inducedthrombocytopeniatest positive63 6 11 45thrombosis device63 2 21 29intracranial aneurysm62 17 20 44metabolic acidosis 62 18 20 39paraparesis 62 1 3 33haemolysis 61 5 11 30splenic veinthrombosis61 11 20 42carotid arteryocclusion60 6 17 44lacunar stroke 60 0 12 37 miller fisher syndrome 60 1 7 42 aneurysm 60 11 13 34 thrombectomy 60 7 25 51 magnetic resonance imaging abnormal 58 1 19 40hypercoagulation 58 3 16 24Data status: 08/20/2021176Identifier Number of deaths Life-threatening incidentsHospitalisier.cerebrovasculardisorder58 11 8 31bundle branch blockright57 0 14 28hemianopia 57 1 9 29hypertensiveemergency57 1 8 31urosepsis 56 20 9 39sopor 56 11 2 12csf proteinincreased55 0 9 50angiogram cerebralabnormal 55 2 27 53lactic acidosis 54 12 9 39craniocerebralinjury53 8 6 26hepatic veinthrombosis53 7 12 37blood countabnormal52 0 6 19white matter lesion 52 0 8 37neutrophil countdecreased51 1 6 14haemorrhagicdiathesis50 2 6 12coma scaleabnormal50 13 17 30personality change 49 6 1 17brain death 49 42 14 23emphysema 47 9 3 15pulmonary haemorrhage 47 12 16 31venous occlusion 46 2 4 27vena cavathrombosis46 6 16 29myocardial necrosismarker increased45 0 7 32coronary arterystenosis45 6 13 29intraventricularhaemorrhage45 12 19 31carotid arterystenosis44 5 7 36cerebral smallvessel ischaemicdisease44 2 4 31cardiac ventr icular 44 6 21 34Data status: 08/20/2021177Identifier Number of deaths Life-threatening incidentsHospitalized.thrombosisgastric aemorrhage44 10 9 21pulmonary arterythrombosis43 11 14 31thrombotic stroke 43 4 14 35computerisedtomogram headnormal41 1 8 37cardiovascularinsufficiency40 2 5 8visceral venousthrombosis40 6 18 30right ventricular failure39 9 15 24bundle branch blockleft38 4 6 16apraxia 38 2 9 23basilar arterythrombosis37 9 16 24blood fibrinogendecreased37 2 16 24aortic aneurysm 37 12 4 15cardiopulmonaryfailure36 32 1 7retinal arterythrombosis36 0 2 4haemorrhagictransformationstroke35 12 13 26pupil fixed 34 8 7 12activated partialthromboplastin timeshortened33 1 9 18embolism arterial 33 1 11 23blood lactic acidincreased33 7 9 13brain stem stroke 32 4 8 19axillary veinthrombosis32 3 8 13mesenteric arterythrombosis32 11 7 18 portosplenomesenteric venous thrombosis 31 3 11 27 ventricular arrhythmia 31 2 12 11 data status: 20.08.2021178 identifier number of deaths Life-threatening incidentsHospitalizerenal vein thrombosis 29 3 13 19 international normalized ratio abnormal 28 1 2 7 cavernous sinus thrombosis 28 7 11 18 atrial thrombosis 27 4 15 21 thrombotic microangiopathy 25 3 12 19 vascular stent thrombosis 22 2 11 17 ovarian vein thrombosis 21 3 6 13 international normalized ratio 20 0 6 1 3thrombotic cerebral infarction19 1 1 16seizure cluster 17 0 2 6splenic thrombosis 16 2 4 10thrombosismesenteric vessel16 5 5 10internationalnormalized ratiofluctuation16 0 1 2ophthalmic arterythrombosis15 0 0 4renal arterythrombosis15 0 3 12splenic arterythrombosis14 1 3 13vascular graftthrombosis14 2 3 9pulmonary venousthrombosis13 0 4 7thrombosedvaricose vein13 0 0 0brain stemthrombosis13 3 4 8vert ebral arterythrombosis13 0 2 9hepatic vascular thrombosis12 3 3 9subclavian arterythrombosis11 1 4 7injection site thrombosis10 0 0 2data status: 08/20/2021179Identifier Number of deaths Life-threatening incidentsHospitalize
